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Biocogent, LLC | 25 Health Sciences Dr. • Stony Brook, NY 11790 • 631.638.1300 • info@biocogent.com • product: TensylPro™

Resilience, Radiance and Firmness - Powered by Collagen & DEJ

a novel  combination of two 
botanically sourced ingredients, Rumex acetosella and Pinus 
massoniana; Boost elastin and collagen production

TensylPro™ is a next-generation, clinically proven active ingredient that harnesses the synergistic co-extraction of two powerful botanicals to restore and reinforce the skin’s foundational architecture for lasting vitality.

TensylPro™ combines two synergistic botanicals, Rumex acetosella and Pinus massoniana, to restore and reinforce the architecture of the skin. Designed to promote skin health by supporting the dermal-epidermal junction (DEJ) and targeting chronic inflammation, TensylPro™ stimulates both collagen and elastin production, while also rebuilding essential proteins for long-term anti-aging benefits. TensylPro™ provides comprehensive skin health and rejuvenation by promoting firmer, plumper, and more resilient skin. The synergistic blend of this dual botanical extract makes TensylPro™ a targeted solution for skincare formulations designed to promote healthy skin aging, skin firming, and smoothing benefits while helping to counteract inflammation and wrinkle formation.

Revitalize your skin at the DEJ—where health, youth, and longevity begin!

of treated panelists saw improvement of several visible signs of aging/wrinkle reduction starting at 4 weeks
genes upregulated to support skin strength and structure
inflammatory mediators inhibited
strengthens the DEJ

TensylPro™

Product ID: R10131

Suggested Use Level: 0.5-5%

Propanediol (and) Water (and) Pinus massoniana bark/Rumex acetosella flower, leaf, stem extract (and) Caprylhydroxamic Acid (and) 1,2–Hexanediol


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Applications

an ideal ingredient for skincare formulations targeting:
• Anti-aging & Longevity: Reducing wrinkles and fine lines
• Firming & Lifting: Enhancing skin structure and elasticity
• Collagen Boosting: Strengthening the skin’s foundational support
• Skin Smoothing: Refining texture and improving hydration

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Last Updated: February 4, 2026

COL3A1 expression

Treatment with 0.075% TensylPro™ led to an increase in COL3A1 and COL4A1 protein expression by 26% and 121% relative to untreated controls, respectively. In both cases, this was as effective or better than TGFβ1, a known inducer of collagens. This demonstrates that TensylPro™ is able to upregulate key proteins whose degradation is directly related to skin aging.

Gene expression profiling was conducted in ex vivo human skin explants. The skin explants were topically treated with 0.3% TensylPro™ for 9 days. Untreated skin explants were used as a control. Results showed upregulation of 22 genes targeting ECM synthesis, tissue morphogenesis and regulation of collagen fibril organization, tissue repair, and strengthening the dermal-epidermal junction. These results make TensylPro™ a powerful dermal-epidermal junction active ingredient.

Proven Performance | Visible Results | Elevated Beauty

Clinically tested and consumer validated, TensylPro™ delivers comprehensive firming and wrinkle reduction benefits — restoring the strength, elasticity, and smoothness of youthful skin.

Elasticity (ElastiMeter™)

Continuous, statistically-significant improvement in skin elasticity and resilience through 12 weeks.

Claim: Improves skin elasticity and resilience for a firmer, more lifted appearance.

Smoothness (Expert Grading)

Up to 19% improvement at 12 weeks, with nearly 100% of participants showing measurable improvement.

Claim: Leaves skin visibly smoother, and rejuvenated.

Firmness (Cutometer®)

A 9.8% improvement at 4 weeks, increasing to 16.5% by 12 weeks, with 100% of subjects showing measurable improvement.

Claim: Refines skin texture and restores a smooth, uniform feel for a visibly renewed, more polished complexion.

Crow’s Feet

Significantly reduced the appearance of crow’s feet - by 10.2% at 4 weeks, 14.4% at 8 weeks, and 15.7% at 12 weeks. 97% of participants showed visible improvement, revealing a smoother, more youthful eye contour.

Claim: Smooths the appearance of crow’s feet and restores youthful eye contours.